Type: Package
Package: invivoPKfit
Title: Fits Toxicokinetic Models to In Vivo PK Data Sets
Version: 2.0.2
Date: 2025-8-26
Authors@R: c(person("John", "Wambaugh", email = "wambaugh.john@epa.gov", 
             role = c("aut", "cre"), comment = c(ORCID = "0000-0002-4024-534X")),
             person("Caroline", "Ring", email = "Ring.Caroline@epa.gov", 
             role = c("aut"), comment = c(ORCID = "0000-0002-0463-1251")),
             person("Gilberto", "Padilla Mercado", role = c("aut"),
             comment = c(ORCID = "0000-0001-5423-1646")),
             person("Chris", "Cook", role = c("aut"))
             )
Author: John Wambaugh [aut, cre] (ORCID:
    <https://orcid.org/0000-0002-4024-534X>),
  Caroline Ring [aut] (ORCID: <https://orcid.org/0000-0002-0463-1251>),
  Gilberto Padilla Mercado [aut] (ORCID:
    <https://orcid.org/0000-0001-5423-1646>),
  Chris Cook [aut]
Maintainer: John Wambaugh <wambaugh.john@epa.gov>
Description: Takes in vivo toxicokinetic concentration-time data and fits
    parameters of 1-compartment and 2-compartment models for each
    chemical. These methods are described in detail in "Informatics for Toxicokinetics" (2025).
License: GPL-3
Depends: R (>= 4.1.0)
Imports: cli, dplyr, ggplot2, httk, MASS, Matrix, mirai, numDeriv,
        optimx, PK, pracma, purrr, rlang, stats, scales, tibble, tidyr
Suggests: cowplot, knitr, RColorBrewer, rmarkdown, stringr, testthat
        (>= 3.0.0), glue, tidyverse
VignetteBuilder: knitr
Config/testthat/edition: 3
Encoding: UTF-8
LazyData: TRUE
NeedsCompilation: no
Packaged: 2025-08-26 13:29:28 UTC; GPADILLA
RoxygenNote: 7.3.2
Repository: CRAN
Date/Publication: 2025-08-26 14:10:02 UTC
Built: R 4.5.3; ; 2026-07-14 13:05:09 UTC; windows
